NFL Week 6 TNF Preview, Prediction, Picks

For week 6 of TNF, the Seahawks will host the 49ers at Lumen Field, live at 8:15PM ET! Check out this edition of The Betting Report for all the betting alpha you need to lock in some winning trades tonight!

⏰ 8:15PM ET - 49ers vs. Seahawks

Pre-Match Overview

The Seattle Seahawks (3-2) are facing off against the San Francisco 49ers (2-3) for the NFL’s Primetime TNF matchup. The moneyline odds on SX Bet are set at Seahawks 2.65 (+165) and 49ers 1.57 (-175) with the spread standing as Seahawks +3.5 at 1.94 (-106) and 49ers -3.5 at 2.01 (+101).

The Seahawks are 1-3-1 (25%) against the spread compared to the 49ers at 2-3-0 (40%). Pay attention to the total line as the Seahawks are 4-1-0 (80%) and the 49ers are 3-2-0 (60%) on the over this season. SX Bet has the total set to 48.5 with odds of 1.93 (-108) for the over and 1.92 (-109) for the under.

Preview

Seattle is facing its third game in 11 days, further complicating their injury issues. Cornerback Riq Woolen, outside linebacker Uchenna Nwosu, and defensive tackle Byron Murphy have already been ruled out. Additionally, safety Julian Love and outside linebackers Derick Hall and Boye Mafe are listed as questionable. The Seahawks are seventh in the NFL in total offence and third in passing offence. Quarterback Geno Smith regularly puts his team in position to succeed offensively. The West Virginia product is first in the league in passing yards with five passing touchdowns. He's racked up 280-plus yards in four straight games.

After leading the Arizona Cardinals by 13 points at halftime, the 49ers were unable to score in the second half, allowing the Cardinals to mount a comeback and secure a win on the road. Maintaining leads has been a recurring issue for San Francisco, and it's a problem they need to address quickly if they want to be contenders. After five games, San Francisco ranks second in total offence, fourth in passing offence and eighth in rushing offence. Quarterback Brock Purdy ranks fourth in the NFL in passing yards.

Prediction

Expect the Seahawks losing streak to continue into week 7 after facing off against a heavyweight offence in a mid-scoring game that does not reach the over.

🔒 Spread: 49ers -3.5